癌症科学理学学士荣誉学士

课程模块Modules

• 年一Year one
• 年二Year two
• Year three

6 modules

• Genetic polymorphisms and genome-wide association studies
• Chemical, viral, and radiation induced DNA damage and tumourigenesis
• 癌症细胞基因组学与基因组项目Cancer cell genomics and the 100,000 genome project
• Cancer cell transcriptomics and epigenomics
• 精准医学癌症治疗Precision medicine in cancer treatment

2 modules

• read and critically analyse scientific literature
• produce a poster that summarises the results of your work and present in a conference-type setting

5 modules

• Current treatments and outcomes for a range of paediatric cancers
• The principles behind chemotherapy, radiotherapy, and surgery in childhood cancer
• How improved understanding of the underlying biology is driving novel treatment strategies
• An in-depth consideration of preclinical approaches to developing novel treatment strategies
• Issues with translating findings in the laboratory to clinical trials and finally standard of care
• The broader effects of paediatric cancer on families and independent living for survivors
• 创新技术Innovative technologies
• Discovery biology (phenotype analysis) - genetic screening using CRISPR, shRNA, and siRNA
• Transcriptomics - RNA seq, spatial transcriptomics, and single cell sequencing
• Epigenomics - ChIP seq, RIME, Proteomics, Metabolomics including spatial metabolomics
• 人工智能与成像Artificial Intelligence/imaging
• 3D in vitro tissue culture approaches: organoids, patient tissue explants, and tumour spheroids
• Bioengineering in 3D cancer models and description of synthetic niches mimicking the tumour microenvironment
• Drug screening using in vitro models and consideration of pharmacokinetics (including for drug-resistant cells)
• 相I与相二临床试验Phase I and Phase II clinical trials