药物发现理学硕士

必修Core modules

• Physicochemical properties
• ADME
• Drug-target interactions
• Quantitation of Drug Effects
• 多样性分子药物目标The Diversity of Molecular Drug Targets
• Cell Signalling Modalities and Their Relationship with Tissue and Organismal Behaviours
• Pharmacotherapy of Major Human Diseases and Disorders
• Retrosynthetic analysis
• Medicinal Chemistry Case Studies
• Group coursework on 'Designing a SAR Study’
• The key organs in the body influencing drug pharmacokinetics
• The influence of pharmacokinetics in the drug discovery process
• ADME and toxicology
• In-vitro, in-vivo and in silico methods available for quantitative pharmacokinetics
• The role of drug transporters in ADME
• 制剂选择药物发现Formulation selection in drug discovery
• The prediction of human pharmacokinetic parameters and simulation of plasma concentration- time profiles
• The role of the Regulatory Authorities in drug development
• 计算化学Computational chemistry
• 合成有机化学Synthetic organic chemistry
• 分析化学Analytical chemistry
• Quantitative pharmacodynamics
• Quantitative pharmacokinetics
• Development of electroceuticals for treating cancer
• Visualising cannabinoid receptors in Drosophila
• Targeting antiretroviral drugs for better treatment of HIV/AIDS
• Biased Agonism: Mathematical Modelling of Ligand Bias
• The potential role of pomegranate in altering vascular function
• Establishing a nanoBRET assay for the multidrug pump ABCG2
• Predicting propylene glycol CNS concentration with PBPK modelling